Hot Topics Banner

Long-term anti-TNF therapy: Efficacy and safety considerations

Program overview

Long-term maintenance therapy with anti-TNFs has been associated with improved long-term outcomes. However, patient and healthcare provider concerns may lead to treatment interruption or withdrawal. It is therefore important to ensure that any decision to discontinue therapy (or step-down) is fully informed, and the patient and healthcare provider are aware of the benefits and risks of long-term anti-TNF therapy. This Hot Topic will provide a critical evaluation of some of the things that should be considered regarding the long-term use of anti-TNF therapy.

Target audience

This activity has been designed to meet the educational needs of gastroenterologists and registered nurses involved in the care of patients with inflammatory bowel disease (IBD).

Release date: February 17, 2016
Expiry date: February 17, 2017

Learning objectives

After completing this activity, the participant should be better able to:

  • Summarize the issues concerning long-term anti-TNF therapy
  • Evaluate when it is appropriate to stop anti-TNF therapy, or to step-down therapy
  • Provide appropriate care and counsel for patients and their families.

Faculty

Nabeel Khan, MD

Clinical Assistant Professor of Medicine
University of Pennsylvania Perelman School of Medicine
Chief, Section of Gastroenterology
Philadelphia VA Medical Center
Philadelphia, PA





Biography

Nabeel Khan received his medical degree from King Edwards Medical College in Pakistan. He went on to complete his residency in internal medicine at Mercy Catholic Medical Center in Philadelphia, PA. Dr. Khan completed his fellowship in Gastroenterology from Louisiana State University. He was trained in ERCP's and has special interest in motility studies. Dr. Khan worked in a private practice group in Memphis, TN, and later became an Instructor at SUNY Brooklyn School of Medicine.

Close Biography

Syllabus disclosure statement

Disclosure of conflicts of interest

Postgraduate Institute for Medicine (PIM) requires instructors, planners, managers and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to PIM policy. PIM is committed to providing its learners with high quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

Name Reported Financial Relationship
Nabeel Khan Consulting fees: GI Health Foundation
Research: Luitpold Pharmaceuticals, Takeda

The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

The following PIM planners and managers, Trace Hutchison, PharmD, Samantha Mattiucci, PharmD, CHCP, Judi Smelker-Mitchek, RN, BSN, and Jan Schultz, RN, MSN, CHCP, hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

The following SCI planners and managers, Ian Morgan, MSc, and Elena Urso, BSc, hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity or any amount during the past 12 months.

Accreditation

Physician Continuing Education

Accreditation statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Postgraduate Institute for Medicine and Strategic Consultants International. The Postgraduate Institute for Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Credit designation

The Postgraduate Institute for Medicine designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Education

Credit designation

This educational activity for 0.75 contact hours is provided by Postgraduate Institute for Medicine.

Accreditation statement

Postgraduate Institute for Medicine is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

Estimated time to complete activity: 45 minutes

Disclosure of unlabeled use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Method of participation and request for credit

There are no fees for participating and receiving CME/CE credit for this activity. To successfully earn credit, participants must complete the activity online during the valid credit period. Follow these steps to earn CME/CE credit:

  1. Read the target audience, learning objectives, and author disclosures.
  2. View the educational content online
  3. Upon completion of the activity, complete the online posttest and Activity Evaluation to provide feedback for future programming.

Upon successful completion of the posttest, with a passing score of 75% or better, and the online evaluation, you will have immediate access to a CME/CE certificate to print or save for your files. We strongly encourage you to complete the Activity Evaluation to provide your feedback for future programming.

If you have any questions regarding the CME/CE certification for this activity, please contact Postgraduate Institute for Medicine at: information@pimed.com
or (303) 799-1930.

Media: internet

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.


This activity is jointly provided by Postgraduate Institute for Medicine
and Strategic Consultants International
PIM Logo SCI Logo
This activity is supported by an independent educational grant from
Takeda Pharmaceuticals International, Inc., US Region, UCB, and Prometheus
Link to CME Information View Program
Apply for CME Credit